Here's a pic for an HL2 mod called Armageddon strain. Its based off of the Andromeda strain. I don't know if the people doing it will ever make it happen, but I thought I'd contribute anyway.
This is about 1 hour and 15 min into it. He's supposed to be running from someone. I thought I'd put the other guys hand in the rear of the frame. It would go along with an environment sketch showing both figures in mid chase.
The color one is a bit more rough. I still have a really hard time with color, so its a bit bland.
the anatomy of the left arm of the dude running seems a bit too short. I'd get your skeletons down before dressing them, it will help you achieve a more believable figure.
Is this a concept for the game? Lets see more designs!
keep it comin