Quietly, another major breakthrough in regenerative medicine has been reported. A five-hundred fold increase in the ability to generate induced pluripotent stem cells in the lab.
Full story: http://www.physorg.com/news/2011-04-...tem-cells.htmlBefore this procedure, which uses microRNAs instead of the four key transcription factor genes, for every 100,000 adult cells re-programmed, researchers were able to get a small handful of iPSCs, usually less than 20. Using the microRNA-mediated method, they have been able to generate approximately 10,000 induced pluripotent stem cells from every 100,000 adult human cells that they start with. MicroRNAs (miRNAs) are short RNA molecules that bind to complementary sequences on messenger RNAs to silence gene expression.