For selling original art, yes, since I like to see it hanging in their home rather than sitting in my studio.

For commissions, generally no, because I don't have time for that kind of stuff and it often turns out to be boring, complicated, fussy, or otherwise not fun. I will sometimes do something cheap for them if it's super-easy, like a quick sketch of their dog or something, but anything that takes more than an hour or two I will turn down or ask for a normal price.