Checkout the online graphic design software at Fatpaint.com
Fatpaint is free and has support for doing layered brush painting, vector drawing, photo editing, page layouts and printing on Zazzle merchandise. It runs inside the browser and as far as I know, it's the only flash based graphic editor to fully support pressure sensitive pen tablets. I have seen most of the other online graphic programs, and in my opinion, Fatpaint is the best one for drawing and painting online with brushes, and for doing page layout.
Besides all the advanced features, Fatpaint has built-in, lots of graphical content, such as 980+ fonts, 3000+ vector clip arts that can be used as brushes, and 15.000 public domains images. It's easy to search for images because of the extensive internet searching features.
To top it all, Fatpaint is integrated with Zazzle.com, a world leading custom printed products company. So while you are making graphics, it's easy to preview it on most of the zazzle products, such as the t-shirts and mugs. The merchandise preview and ordering features are right next to the canvas, so at the press of a button you images can be displayed on the Zazzle products.
Those looking for a full featured online program for drawing and painting with their pressure sensitive pen tablets, now finally have a choice.
I spent 5 years developing the application and I would like to get some feedback from you, so any suggestions and ideas for improving the software would be highly appreciated.