Next, go to Start - Programs - Wacom Tablet - Wacom Tablet Preference File Utility and Delete all your preferences. Reboot your PC. Yes it wipes out all your former shortcuts.
If you are too lazy to program your shortcuts again, you can save a copy of the Wacom_Tablet.dat into a directory and name them. This is also handy for other programs that can't read more than one Tablet installed, like Sai Paint.